Parathyroid adenoma

Case contributed by Ammar Ashraf
Diagnosis certain

Presentation

High parathyroid hormone and calcium levels.

Patient Data

Age: 70 years
Gender: Female
ultrasound

Normal size thyroid gland with heterogeneous parenchymal echotexture.

Heterogeneous hypoechoic oval nodule measuring 1.6 x 3.3 cm containing small cystic areas and lying adjacent to the posterior aspect of the left thyroid lobe. No calcifications. Mild internal vascularity on color Doppler.

ct

Ovoid nodule measuring 1.5 x 3.0 x 4.2 cm adjacent to the posterosuperior aspect of the left thyroid lobe, of soft-tissue attenuation on non-contrast CT. It shows heterogeneous enhancement during the arterial phase and some washout during the venous phase. Multiple small non-enhancing cystic/necrotic areas are seen within it. No calcifications. Hypertrophied artery entering the lower pole, a branch of the left inferior thyroid artery. Normal right parathyroid gland region.

Normal size thyroid gland showing normal hyper-attenuation on non-contrast CT and mildly heterogeneous parenchymal enhancement.

Multiple normal small bilateral lymph nodes.

Histopathology

Photo

Histopathology of the left parathyroidectomy specimen showed parathyroid gland adenoma with cystic degeneration.

Case Discussion

Ultrasound (US) and CT scan showed an enlarged left superior parathyroid gland adenoma. Multiple cystic foci noted within the lesion on both US and CT scan. The lesion was resected and the histopathology confirmed parathyroid adenoma with cystic degeneration.

Attenuation on non-contrast CT is lower than that of normal thyroid tissue as the parathyroid gland do not concentrate iodine.

This adenoma is easy to detect because of its size and location. Parathyroid adenomas are often very small and can be ectopic.

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