Presentation
Confusion and forgetfulness.
Patient Data
Well defined uniform hyperdense midline lesion involving the corpus callosum with associated bilateral cerebral white matter edema.
MRI confirms CT findings of uniformly enhancing solid lesion of the corpus callosum in the midline showing restricted diffusion and associated perilesional edema.
Case Discussion
The imaging appearance for primary CNS lymphoma is of a CT hyperdense avidly enhancing mass, with T1 hypointense, T2 iso- to hypointense, vivid homogeneous gadolinium-enhancing lesion(s) with restricted diffusion on MRI, and exhibiting subependymal extension and crossing of the corpus callosum