Thymoma and myasthenia gravis

Case contributed by Shervin Sharifkashani
Diagnosis almost certain

Presentation

History of eyelid ptosis and chest pain. Known myasthenia gravis.

Patient Data

Age: 25 years
Gender: Female

There is a well-defined solid mass lesion in the anterior superior mediastinum prevascular region. No obvious or gross mediastinal lymph nodes.

Case Discussion

Biopsy was done. Non-invasive thymoma was reported by the pathologist. MRI and MDCT are both practical for thymoma staging and follow-up.

The concurrence of myasthenia gravis, eyelid ptosis, and thymoma is relatively common, which is why imaging the mediastinum is important in the evaluation of ptosis cases. The main differential diagnosis of anterior mediastinal masses is thymoma and germ cell tumors.

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