Toxic megacolon

Case contributed by Michael P Hartung
Diagnosis almost certain

Presentation

Recent surgery, abdominal pain, diarrhea.

Patient Data

Age: 35 years
Gender: Male
ct

Nasogastric tube. Small ascites. Tremendously thickened colon and rectum with submucosal edema/thumbprinting, thickened haustra, and serosal/mucosal hyperemia. Partially occlusive thrombus within the right internal iliac artery.

Case Discussion

Dramatic findings of severe pancolitis characteristic of toxic megacolon, likely related to recent surgery and antibiotic usage resulting in infection from Clostridioides difficile. Colitis this severe needs aggressive supportive care and potential total colectomy due to the risk of perforation. 

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