Unilateral anterior cerebral artery (A1 segment) aplasia

Case contributed by Ammar Ashraf
Diagnosis certain

Presentation

Confusion and left-sided weakness since yesterday. History of minor stroke a year ago.

Patient Data

Age: 70 years
Gender: Male
  • acute right frontal intracerebral bleed with mild surrounding vasogenic edema and a mild mass effect on the adjacent frontal horn of the right lateral ventricle. Another tiny linear hyperdensity (likely hemorrhage) measuring approximately 4 mm is noted in the right posterior frontal lobe. No skull bone fracture. There is no CT evidence of a recently established territorial infarction. Age-related involutional changes in the brain parenchyma, small vessel-induced periarticular deep white matter ischemic changes, and a small old lacunar infarct in the left basal ganglia

  • common origin of the brachiocephalic trunk and left common carotid artery from the aortic arch (bovine arch -- anatomical variant) and direct origin of the dominant left vertebral artery from the aortic arch (also an anatomical variant)

  • a few tiny calcifications in the proximal left internal carotid artery; otherwise, normal course, caliber, and contrast opacification of bilateral common carotid arteries, carotid bulbs, internal carotid arteries, and vertebral arteries in the neck

  • non-visualized/aplastic A1 segment of the right anterior cerebral artery with a patent and well-opacified A2 segment of the right anterior cerebral artery, which is likely opacified from the contralateral circulation via the anterior communicating artery

  • morphology of the remaining intracranial vessels is unremarkable.

Case Discussion

A CT angiography of the cerebral arteries was performed to rule out any underlying vascular abnormality. The CTA was negative for any vascular malformation; however, it showed a few anatomical variants:

  • absent A1 segment of the right ACA, an anatomical variant seen in 10% of the individuals

  • dominant left vertebral artery, an anatomical variant seen in 45% of the individuals

  • left vertebral artery arising directly from the aortic arch, an anatomical variant seen in 6% of the individuals

  • common origin of the brachiocephalic trunk and the left common carotid artery from the aortic arch (bovine arch); the most common variant of the aortic arch

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