Glioblastoma NOS (multifocal)

Discussion:

This case illustrates the characteristic imaging findings in glioblastoma (GBM). The most common imaging appearance of GBM is a large mass located in the supratentorial white matter. On CT it is typically a heterogeneous mass, with central areas of necrosis delineated by a thick irregular wall. There is surrounding extensive vasogenic edema with resultant mass effect. On MRI, the lesions are usually hypointense on T1-weighted imaging, and hyperintense on proton density and T2-weighted images. 

 

The patient was offered further treatment with radiotherapy and chemotherapy, although declined, dying within six months of his diagnosis. 

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