This is a CNS lymphoma. The patient has a history of diffuse large B cell lymphoma. He was treated with several courses of rituximab, methotrexate, procarbazine, vincristine (R-MPV) and intraventricular rituximab.

Despite treatment, the patient had progressive right sided hemiataxia, dysarthria, and headaches. An MRI showed progression of right cerebellar lesion and concern for hydrocephalus due to ventricular involvement. He continued to have worsening mental status. He eventually expired due to complications related to therapy.

Co-author:
Jun Yang