The patient underwent cold steel and shaver excision of the laryngeal lesion under general anesthesia.
Histology: numerous deposits of homogenous eosinophilic material which stained salmon pink on congo red and showed apple-green birefringence, confirming amyloidosis.
Case discussion
Amyloidosis is very rare and represents a heterogeneous group of disorders marked by abnormal protein formation and deposition which can cause organ failure and death. Up to 20% involve the head and neck, the larynx being the most common site of disease, representing 0.2-1.2% of all benign laryngeal tumors. Symptoms depend on the size and specific location of the deposit and may include dysphonia, dysphagia or exertional dyspnea.