What is the differential diagnosis based on the CT images?
Liver abscess and necrotic malignancy would be differential considerations.
CT of the abdomen and pelvis with IV and oral contrast shows an irregular peripherally enhancing lesion in the right hepatic lobe, extending to the hepatic dome. There is edema around the lesion, suggestive of a "double target sign". This is a large single lesion. No other lesion is seen in the abdomen or pelvis. There is colonic diverticulosis without acute diverticulitis. No colonic wall thickening or pericolic fat stranding is seen to suggest colitis.