Atypical meningioma - brain invasion

Discussion:

The patient went on to have a resection. 

Histology

Paraffin sections show a moderately hypercellular meningioma. This has a well developed syncytial architecture. Moderate numbers of calcified psammoma bodies are also noted. Tumor cells have uniform nuclear features. No mitotic figures or areas of necrosis are identified. Invasion into a small amount of attached brain tissue is identified.

FINAL DIAGNOSIS: atypical meningioma due to brain invasion (WHO Grade II)

Discussion

Unfortunately, imaging struggles to accurately predict the grade of meningiomas or whether or not there is brain invasion, and the presence of vasogenic edema is not a good indicator that invasion is present. 

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