Liposarcomas are malignant tumors of mesenchymal origin, mostly found in the subcutaneous region, extremities, and retroperitoneum. Myxoid liposarcomas are the second most common subtype of liposarcoma, most commonly occurring in the extremities ¹. Primary mesenteric liposarcomas are extremely rare ^2-3.

This patient had primary mesenteric myxoid liposarcoma, which is a rare location for this subtype. Myxoid liposarcoma has high water content due to the abundant myxoid matrix and appears hypodense on CT ¹. In this case, the enhancing septations and traversing vessels helped to distinguish it from a benign cystic mass.