What is one of the major causes of nasal septum perforation?
Granulomatosis with polyangitis.
There are large defects in the nasal septum and nasal cavities concha and ethmoidal air cells with marginal thick mucosa and fluid in remnant air cells of ethmoid sinus and thick medial wall of the maxillary sinuses with fluid and thick mucosa and antral obliteration of maxillary sinuses. Fluid in the right middle ear and mastoid air cells is also noted.