MICROSCOPIC DESCRIPTION: The sections contain cerebral cortex and white matter. There are areas of haemorrhage within both cortex and white matter. Some entrapped neutrophils are seen within the areas of blood. The leptomeningeal and cortical blood vessels appear to contain some amorphous eosinophilic material. B-amyloid immunostain is positive. Many amyloid plaques are also seen in the cortex. No vasculitis is seen. There are no perivascular CD3 or CD20+ lymphocytes. No tumour is identified.
DIAGNOSIS: Brain tissue: Amyloid angiopathy with areas of haemorrhage. No evidence of vasculitis.