Well-differentiated pancreatic neuroendocrine tumors comprise of ∼1-3% of pancreatic neoplasms. Depending on the cell of origin they may be malignant. The treatment of choice for a localized pancreatic head tumor (as in this case) is a Whipple's procedure (pancreaticoduodenectomy).
This tumor was functional (synaptophysin and chromogranin positive). There was not a dominant tissue type and it was not syndromic.