Gliosarcoma

Discussion:

The patient went on to have a resection. 

Histology

Microscopic Description:

Sections show a glial tumor displaying necrosis, vascular proliferation, a spindle cell component (consistent with so-called gliosarcoma), and obvious mitotic activity. The tumor cells display features that range from small cell to gemistocytic characteristics. Blood vessels appear somewhat hyalinized in areas.

Final Diagnosis: gliosarcoma.

Note: This case predates the recent (2016) revision WHO classification of CNS tumors and IDH status is not available. 

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