Pituitary macroadenoma

Case contributed by Hoe Han Guan
Diagnosis almost certain

Presentation

Headache, blurred vision and bilateral lower limb weakness for one week.

Patient Data

Age: 55 years
Gender: Female
ct

Soft tissue attenuating mass, which is most likely arising from the sella turcica with predominant suprasellar extension, exerts significant mass effect onto optic chiasm and bilateral foramen of Monro superiorly. Due to the compression onto the foramen of Monro, disproportionate dilatation of bilateral lateral ventricles with periventricular lucency represents acute obstructive hydrocephalus.

The sellar soft tissue mass has "snowman" or "figure of eight" configurations on coronal view.

mri

Well-circumscribed lobulated sellar mass (originated from the sella turcica as evidenced by upwards displacement of diaphragmatic leaflets, which themselves constrict onto the mass forming the characteristic snowman configuration) causes expansion of sella turcica. It has suprasellar extension.

Annotated image

Annotated images show the importance of diaphragma sella/leaflets to guide radiologists the most likely origins of the sellar/suprasellar mass.

Case Discussion

Patient went on to have trans-sphenoidal surgery and histopathological examination confirmed pituitary macroadenoma.

This case demonstrates the usefulness of assessing the displacement of diaphragmatic leaflets to formulate the possible differential diagnoses for sellar/suprasellar mass.

The mass effect on adjacent structures such as optic chiasm, third ventricle, foramen of Monro, and midbrain superiorly should be reported.

Assessment of cavernous sinuses and encasement of cavernous segment of internal carotid arteries is important for pre-operative surgical planning.

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