Posterior reversible encephalopathy syndrome (PRES)

Case contributed by Farah Alyetama
Diagnosis almost certain

Presentation

Drowsiness, seizures, and a severe headache with a hypertensive emergency

Patient Data

Age: 40 years
Gender: Male

 Areas of increased signal intensity are seen in the left subcortical cerebral hemisphere, both frontoparietal and temporal in location. They are displaying high signal intensity on FLAIR and T2-weighted images.

They also display a non-restricted diffusion pattern with a hypointense signal on DWI and an increased signal on ADC images.

Case Discussion

Posterior reversible encephalopathy syndrome (PRES) is a clinical syndrome characterized by typical neurological symptoms more commonly in patients with hypertension, supported by neuroimaging evidence of vasogenic edema localized to the posterior cerebral white matter. While the edema is usually bilateral, isolated involvement of one cerebral hemisphere can be seen, as well as involvement of the frontal lobe and cortex.

The patient was treated for hypertension and received anti-seizure medications. A follow-up MRI was scheduled after 3 weeks.

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