Presentation
Forgetfulness for one year but still able to perform activity of daily living.
Patient Data
Global cortical atrophy (GCA) is GCA 3, where severe end stage atrophy throughout the complete cerebrum bilaterally.
Case Discussion
Overall MR imaging features are suggestive of vascular dementia (small vessel disease, strategic infarction at bilateral thalami- especially the right medial thalamic nucleus infarcts are highly associated with cognitive dysfunction). As the MTA score is 3 for the patient's age of 65 years old, the possibility of concurrent early Alzheimer's disease should be considered.
Proper assessment of the cognition is recommended as if only affecting the memory, it will be termed mild cognitive impairment (MCI) but if more than 2 cognitive domains, it is termed dementia.
The microhaemorrhages are likely to be related with hypertension due to the bilateral thalami location. Differential includes cerebral amyloid angiopathy.
Unable to process the form. Check for errors and try again.