Presentation
Progressively worsening headaches. Potential seizure-like activity.
Patient Data
Age: 6 years
Gender: Male
From the case:
Ganglioglioma
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Case Discussion
The patient had a left-sided craniotomy for resection of the left temporal mass using neuronavigation.
Histology
Gross pathologic examination revealed tan and irregular tissue. Histologically, there were numerous cells with voluminous pink cytoplasm. Immunohistochemistry demonstrated that the lesion was uniformly positive for GFAP and P53. A small portion of the mass was highlighted by NeuN. Chromogranin and synaptophysin highlighted the ganglionic component. Neurofilament and CD34 was largely negative. The Ki-67 was low.
Final diagnosis: ganglioglioma in the left temporal lobe.
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